Bench To Bedside

Bench to Bedside Outline A. What is remove to bedside look for? * Described as test and error process where physician researchers find new-fashioned research in the laboratory and then do clinical streaks on patients * Most of these patients be not pieces ab initio; researchers unremarkably tests on animals first before injecting the dose into human patients B. What atomic number 18 some types of terrace to bedside research? * Basic research- they break up jail cell structure of cells and try to determine whether they argon cancer cells or not. If they find some strange they delight it to * Preclinical- is the actual work that is through in the lab. There are two types of preclinical research called in vitro and in vivo. * In vitro means in glass; tests using cell lines and/or cell cultures contained in petri dishes and test tubes * In vivo means exam with out(p) glass; testing on animals and collect information about(pred icate) the activity of the drug ( cognise as pharmocodynamic testing), as wholesome as absorption, distri hardlyion, excretion known as (pharmacokinetic testing) and toxicity. C. What are the trials of bench to bedside research? * bod 1- judge the drugs and do research. Find out what dose of the drug is uninjured and how it should be given.

* Phase 2- the trial and error part; appreciate the drug and take quantitative Is the drug effective? Does it fill further testing? nail down the dose if these questions have been answered. * Phase 3- Tie the research together. disembodied spirit at pre dicted results and final results. rate the ! efficiency toward the standard of care. past confirm or deny the dose. D. What are some examples of bench to bedside research being done? * One of the first examples that was apply for bench to bedside research was Anti-angiogensis * Folkman who make his idea in 1971, but it wasnt until 2002 that Avastin, the VEGF inhibitior was approved for treating colon cancer * UGA researchers actually plunge a new treatment for...If you deficiency to get a full essay, order it on our website: BestEssayCheap.com

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